WARNING: These algorithms have been developed as a guide to our residents especially for initial empirical therapeutic approach and prophylaxis. They are updated periodically. Recommendations for antimicrobials are based on the local pathogen and resistance profiles in our hospital. Therefore, it is not recommended to apply them in another institution word by word. 

NOTE: The listing of antimicrobial alternatives for the condition with more than one treatment option are listed in descending order of "first, second" in accordance with WHO AWaRe List 2023 , i.e., the first listed antibiotic(s) is the first choice. 

1.1. Diagnosis of sepsis / Septic shock

1.2. Initial Empirical Antimicrobial Treatment in Sepsis/Septic Shock

1.3. Initial Empirical Treatment in the Patient in Sepsis/Septic Shock with low MDR Risk

1.4. Initial Empirical Antimicrobial Treatment in Sepsis/Septic Shock (Type 1 Penicillin Hypersensitivity Present)

1.5. Initial Empirical Treatment in Sepsis/Septic Shock in the Patient with Low MDR Risk (Type I Penicillin Hypersensitivity Present)

1.6. Monitoring Antimicrobial Treatment in Sepsis/Septic Shock

1.7. SOFA score

1.8. Evaluation for Type 1 Penicillin Hypersensitivity

1.9. Quality Indicators for Management of Sepsis/Septic Shock

1.10. TDM Available in the Central Hospital Lab

1.11 WHO AWaRe Antibiotic List